Short Description:
CAS number: 62893-20-3 693878-84-7
Molecular formula: C25H26N9Na08S2 C8H10NNa05S
Chemical structure:
| Basic Information | |
| Product name | Cefoperazone sodium + sulbactam sodium (1:1/2:1) |
| Character | Powder |
| CAS No. | 62893-20-3 693878-84-7 |
| Color | White to light brown powder |
| Shelf Life | 2 Years |
| Grade Standard | Medicine Grade |
| Purity | 99% |
| CAS No. | 62893-20-3 |
| Package | 10kg/drum |
Description
Description:
Cefoperazone sodium + sulbactam sodium (1:1/2:1) is a parenterally-active, β-lactamase inhibitor recently introduced as a 1: 1 combination product with cefoperazone. Like clavulanic acid, the first agent of this type to b e introduced, sulbactam enhances the effectiveness of β-lactam antibiotics against resistant strains.
Usage:
A semi-synthetic β-lactamase inhibitor. It is used in combination with β-lactam antibiotics as antibacterial.
Cefoperazone sodium salt is a cephalosporin antibiotic for inhibition of rMrp2-mediated [3H]E217βG uptake with IC50 of 199 μM. Target: Antibacterial Cefoperazone is a sterile, semisynthetic, broad-spectrum, parenteral cephalosporin antibiotic for intravenous or intramuscular administration. After intravenous administration of 2 g of Cefoperazone, levels in serum rang from 202μg/mL to 375 μg/mL depending on the period of drug administration. After intramuscular injection of 2 g of Cefoperazone, the mean peak serum level is 111 μg/mL at 1.5 hours. At 12 hours after dosing, mean serum levels are still 2 to 4 μg/mL. Cefoperazone is 90% bound to serum proteins.
