Short Description:
CAS number: 64485-93-4
Molecular formula: C16H18N5NaO7S2
molecular weight: 479.46
Chemical structure：
| Basic Information | |
| Product name | Cefotaxime sodium |
| CAS No. | 64485-93-4 |
| Appearance | white to yellow powder |
| Grade | Pharma Grade |
| Storage | Keep in dark place,Inert atmosphere,2-8°C |
| Shelf Life | 2 years |
| Stability | Stable. Incompatible with strong oxidizing agents. |
| Package | 25kg/Drum |
Product Description
Cefotaxime sodium is an organic compound with the chemical formula C16H16N5NaO7S2. It is a third-generation semi synthetic cephalosporin that is less effective against gram-positive bacteria than cefazolin. Enterococcus is resistant to this product, but ineffective against penicillin resistant pneumococcus. It has strong bactericidal activity against gram-negative bacteria and stronger antibacterial effects against Escherichia coli, influenza bacteria, pneumonia bacteria, Proteus mirabilis, and Salmonella than cefoperazone. It has weak or resistant effects on Bacteroidetes fragilis, while Pseudomonas aeruginosa and Enterobacter cloacae are insensitive to this product.
Use
Cefotaxime sodium is a commonly used carbapenem antibiotic, belonging to the third generation of semi synthetic cephalosporins. Its antibacterial spectrum is wider than that of cefuroxime, and its effect on Gram negative bacteria is stronger. The antibacterial spectrum includes Haemophilus influenza, Escherichia coli, Escherichia coli, Salmonella Klebsiella, Proteus mirabilis, Neisseria, Staphylococcus, Pneumococcus pneumoniae, Streptococcus Enterobacteriaceae bacteria such as Klebsiella and Salmonella. Cefotaxime sodium has no antibacterial activity against Pseudomonas aeruginosa and Escherichia coli, but has poor antibacterial activity against Staphylococcus aureus. It has strong activity against Gram positive cocci such as Streptococcus hemolyticus and Streptococcus pneumoniae, while Enterococcus (Enterobacter cloacae, Enterobacter aerogenes) is resistant to this product.
In clinical practice, cefotaxime sodium can be applied to treat pneumonia and other lower respiratory tract infections, urinary tract infections, meningitis, sepsis, abdominal infections, pelvic infections, skin and soft tissue infections, reproductive tract infections, bone and joint infections caused by sensitive bacteria. Cefotaxime can be used as a drug of choice for pediatric meningitis.
